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What changed in Alnylam Pharmaceuticals, Inc.'s latest annual report

In the year ended 31 Dec 2025, Alnylam Pharmaceuticals, Inc.'s revenue rose 65.2% to USD 3.71bn, from USD 2.25bn; shareholders' equity rose 1076.3% to USD 789.18m, from USD 67.09m; cash and cash equivalents rose 71.5% to USD 1.66bn, from USD 966.43m.

Year ended 31 Dec 2025. Source: 10-K filed 12 Feb 2026, read it on SEC EDGAR.

USD 2.25bn to USD 3.71bn

Revenue, up 65.2% year on year

The figures, year on year

Annual figures as reported to the SEC, in US dollars. Changes are calculated from the two values.
ItemYear beforeLatest yearChange
Revenue2.25bn3.71bnUp 65.2%
Net income-278.16m313.75mNot comparable
Total assets4.24bn4.97bnUp 17.1%
Total liabilities4.17bn4.18bnUp 0.1%
Cash and cash equivalents966.43m1.66bnUp 71.5%
Shareholders' equity67.09m789.18mUp 1076.3%

Questions people ask

Did Alnylam Pharmaceuticals, Inc.'s revenue grow last year?

Revenue grew 65.2%, from USD 2.25bn to USD 3.71bn in the year ended 31 Dec 2025.

Is Alnylam Pharmaceuticals, Inc. profitable?

Yes. Net income was USD 313.75m in the year ended 31 Dec 2025. The year before: a net loss of USD 278.16m.

How much cash and debt does Alnylam Pharmaceuticals, Inc. have?

At its latest year end (31 Dec 2025), Alnylam Pharmaceuticals, Inc. reported cash and cash equivalents of USD 1.66bn.

Where do these numbers come from?

From Alnylam Pharmaceuticals, Inc.'s own annual filings with the SEC. Each change is calculated from the reported figures; nothing is estimated.

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Alnylam Pharmaceuticals, Inc. (ALNY) 10-K: what changed year on year | LYNORIQ Insights