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What changed in Madrigal Pharmaceuticals, Inc.'s latest annual report

In the year ended 31 Dec 2025, Madrigal Pharmaceuticals, Inc.'s revenue rose 432.1% to USD 958.40m, from USD 180.13m; long-term debt rose 189.1% to USD 339.88m, from USD 117.57m; total liabilities rose 128.2% to USD 656.90m, from USD 287.86m.

Year ended 31 Dec 2025. Source: 10-K filed 19 Feb 2026, read it on SEC EDGAR.

USD 180.13m to USD 958.40m

Revenue, up 432.1% year on year

The figures, year on year

Annual figures as reported to the SEC, in US dollars. Changes are calculated from the two values.
ItemYear beforeLatest yearChange
Revenue180.13m958.40mUp 432.1%
Net income-465.89m-288.28mNot comparable
Total assets1.04bn1.26bnUp 20.9%
Total liabilities287.86m656.90mUp 128.2%
Long-term debt117.57m339.88mUp 189.1%
Cash and cash equivalents100.02m198.69mUp 98.7%
Shareholders' equity754.38m602.69mDown 20.1%

Questions people ask

Did Madrigal Pharmaceuticals, Inc.'s revenue grow last year?

Revenue grew 432.1%, from USD 180.13m to USD 958.40m in the year ended 31 Dec 2025.

Is Madrigal Pharmaceuticals, Inc. profitable?

Not in its latest year: it reported a net loss of USD 288.28m in the year ended 31 Dec 2025. The year before: a net loss of USD 465.89m.

How much cash and debt does Madrigal Pharmaceuticals, Inc. have?

At its latest year end (31 Dec 2025), Madrigal Pharmaceuticals, Inc. reported cash and cash equivalents of USD 198.69m and long-term debt of USD 339.88m.

Where do these numbers come from?

From Madrigal Pharmaceuticals, Inc.'s own annual filings with the SEC. Each change is calculated from the reported figures; nothing is estimated.

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Madrigal Pharmaceuticals, Inc. (MDGL) 10-K: what changed year on year | LYNORIQ Insights