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What changed in Vaxcyte, Inc.'s latest annual report

In the year ended 31 Dec 2025, Vaxcyte, Inc.'s cash and cash equivalents fell 55.2% to USD 173.96m, from USD 387.88m; total liabilities rose 54.4% to USD 317.21m, from USD 205.50m; shareholders' equity fell 18.8% to USD 2.69bn, from USD 3.31bn.

Year ended 31 Dec 2025. Source: 10-K filed 24 Feb 2026, read it on SEC EDGAR.

USD 387.88m to USD 173.96m

Cash and cash equivalents, down 55.2% year on year

The figures, year on year

Annual figures as reported to the SEC, in US dollars. Changes are calculated from the two values.
ItemYear beforeLatest yearChange
Net income-463.93m-766.63mNot comparable
Total assets3.51bn3.00bnDown 14.5%
Total liabilities205.50m317.21mUp 54.4%
Cash and cash equivalents387.88m173.96mDown 55.2%
Shareholders' equity3.31bn2.69bnDown 18.8%

Questions people ask

Is Vaxcyte, Inc. profitable?

Not in its latest year: it reported a net loss of USD 766.63m in the year ended 31 Dec 2025. The year before: a net loss of USD 463.93m.

How much cash and debt does Vaxcyte, Inc. have?

At its latest year end (31 Dec 2025), Vaxcyte, Inc. reported cash and cash equivalents of USD 173.96m.

Where do these numbers come from?

From Vaxcyte, Inc.'s own annual filings with the SEC. Each change is calculated from the reported figures; nothing is estimated.

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